
Peptides
MOTS-C 20mg
MOTS-c is a mitochondrial-derived peptide (MDP) composed of 16 amino acids that plays a critical role in cellular metabolic regulation. Synthesized within mitochondria, MOTS-c functions by modulating cellular energy balance through pathways involved in glucose metabolism, insulin sensitivity, and cellular stress response. It translocates to the nucleus where it influences expression of genes related to mitochondrial biogenesis and metabolic regulation. Research has shown this peptide to improve exercise capacity, reduce obesity, insulin resistance, osteoporosis, and mitigate metabolic disorders and age-associated diseases.
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- Same-day dispatch before 2 PM PT from British Columbia, Canada
- Free shipping over CA$200
- Batch-specific COA with every lot
- Priced in Canadian dollars
Specification
- Catalogue number
- OP-017
- Purity specification
- >99%
- Fill
- 20mg
- CAS number
- 1627580-64-6
- Molecular formula
- C₁₀₁H₁₅₂N₂₈O₂₂S₂
- Molecular weight
- 2,174.6 g/mol
- Form
- Lyophilized powder
- Solubility
- Soluble in bacteriostatic water
- Shelf Life
- 24 months from date of manufacture
About MOTS-C 20mg
MOTS-c (amino acid sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg) is a newly identified MDP that has been found in the nucleus of cells and in the general circulation, making it a bonafide natural hormone. Research demonstrates it reverses age-dependent insulin resistance in muscles by improving skeletal muscle response to AMPK activation independent of the insulin pathway, increases brown fat function while reducing adipose tissue accumulation and inflammation, targets the methionine-folate cycle to activate AMPK for enhanced fat metabolism, promotes osteoblast survival and differentiation for improved bone integrity through the TGF-beta/SMAD pathway, and is associated with exceptional longevity in certain human populations through a specific genetic variant. Research in heart health shows patients with lower MOTS-c levels have higher endothelial cell dysfunction. This 20mg vial supports extended research protocols investigating metabolic homeostasis, exercise biology, and cellular aging.
Storage and reconstitution
Store lyophilized peptide at -20°C in a dry, dark environment. Reconstitute in bacteriostatic water. Once reconstituted, store at 2-8°C and use within 30 days. Avoid repeated freeze-thaw cycles. Lyophilized powder is stable at room temperature for shipping and short-term storage.
Shipping within Canada
Orders placed before 2:00 PM Pacific on a business day are packed and dispatched the same day. Orders placed after that cut-off, or on a weekend or statutory holiday, are dispatched on the next business day. Parcels leave British Columbia, Canada and travel entirely within the country, so nothing on this order crosses a border, clears customs or is held by CBSA. Orders over CA$200 ship free; see the shipping page for transit times by province.
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